 |
1st Generation |
2nd Generation |
3rd Generation |
4th Generation |
5th Generation |
| Structure |
2 layers
Lipophilic |
 |
|
3 layers
Hydrophilic |
 |
|
3 layers
Powder |
 |
|
4 layers
Capsule-in-
capsule |
 |
|
|
| Concept |
2 layers capsules
Development of encapsulator Reduction of shell ratio |
3 layers capsules
Encapsulate hydrophilic substances Mass production |
3 layers capsules
Development of acid resistance shell Application to ethical drugs |
4 layers capsules
Control of release |
Development of Biocapsule
Incubation and cultivation in capsule |
Development
of function |
Improve stability of content
Encapsulate liquid |
Mixture with products
Burst impact |
DDS
Improvement of compliance |
Deepen DDS
Functional Development of 4 layers capsules |
Semipermeable
membrane
Biotechnology |
| Shell Function |
Solubilty |
Freezing resistance
Heat resistance |
Acid resistance
Control of release |
Solution in mouth
+
Solution in stomach
Control of release |
Semipermeable membrane |
| Content |
Flavor
Functional oil |
Hydrophilic flavor
Fruit juice exstract |
Hydrophilic substance
Bifidus powder |
Functional oil |
Lactobacillus
Yeast
DNA. cell |
| Category |
Food
Quasi-drug
Cosmetics |
Food
Quasi-drug
Cosmetics |
Food
Quasi-drug
Cosmetics
Drug |
Food
Drug |
Biotechnology area
|
| Application |
Chewing gum
Health food
Tooth paste
Instant noodle |
Crystal Dew
Capsule JINTAN
Ice cream |
Bifina
Constipation OTC
Solmiran |
Twin clean
Plum Freshener |
Biotechnology |
